Personally, I use the following rules:
- If something can be set several times per second, make it an RFC.
- If something should be associated with an object, use tno.Set.
- If something should be associated with the channel, use TNManager.SetChannelData.
- If something should be server-wide, and only set by admins (such as configuration data), use TNManager.SetServerData.
For player kills, I wouldn't set them as channel data. That seems like an odd place for something that's player-related. Use tno.Set("kills", 123) instead on the player's avatar.