I just updated my UI from 2.7.0 to 3.0.9, and when I ran the game I was getting an exceptional number of the "updateMassFromShapes: Compute mesh" errors. I got about 450 on start, and would keep getting them every few seconds as I played.
I was baffled, as my UI doesn't contain any quads or other objects that would throw this error.
Finally, after much pulling of hair, I found that NGUI had added a rigidbody to my UI's parent object for some reason. The way my project is structured, there's a parent object for everything in my scene (done for additive loading purposes), so there was a Rigidbody component on the parent of every object in my scene (player, gameplay objects, set dressing ... everything). It was causing errors to be thrown about all sorts of objects that had nothing to do with the UI.
So anyway, if you run into this error, check NGUI's parent object. As soon as I removed the incorrectly-added Rigidbody and UIPanel script (no idea on earth why that was added automatically as well) and saved my scene, everything went back to normal again.