Am I correct in understanding that you seem to have nested panels in there? First, you need to update your NGUI version to the latest. 3.5.6 is very old. Second, are they nested clipped panels? (ie: all of them scroll views?) Keep in mind the scroll views work best with widgets inside them, not other panels. Even when using other sub-panels, you should create a widget container first that would contain the entire sub-panel's region inside it. This way the widget will define the area of your content.