Getting the same thing that kval mentioned. Everything is snapped to the center, but corrects itself when in play mode.
To expand on this, and it may not be related, selecting one of these NGUI elements, such as a label, in the editor results in 22 errors, all:
The serializedObject should not be used inside OnSceneGUI or OnPreviewGUI. Use the target property directly instead.
UnityEditor.GameObjectInspector:OnEnable()
Edit 2: This is another error that occurs when selecting elements:
NullReferenceException: Object reference not set to an instance of an object
UIPanel.get_worldCorners () (at Assets/NGUI/Scripts/UI/UIPanel.cs:616)
UIWidgetInspector.DrawAnchorHandle (.AnchorPoint anchor, UnityEngine.Transform myTrans, UnityEngine.Vector3[] myCorners, Int32 side, Int32 id) (at Assets/NGUI/Scripts/Editor/UIWidgetInspector.cs:335)
UIWidgetInspector.OnSceneGUI () (at Assets/NGUI/Scripts/Editor/UIWidgetInspector.cs:448)
System.Reflection.MonoMethod.Invoke (System.Object obj, BindingFlags invokeAttr, System.Reflection.Binder binder, System.Object[] parameters, System.Globalization.CultureInfo culture) (at /Users/builduser/buildslave/mono-runtime-and-classlibs/build/mcs/class/corlib/System.Reflection/MonoMethod.cs:222)
Rethrow as TargetInvocationException: Exception has been thrown by the target of an invocation.
System.Reflection.MonoMethod.Invoke (System.Object obj, BindingFlags invokeAttr, System.Reflection.Binder binder, System.Object[] parameters, System.Globalization.CultureInfo culture) (at /Users/builduser/buildslave/mono-runtime-and-classlibs/build/mcs/class/corlib/System.Reflection/MonoMethod.cs:232)
System.Reflection.MethodBase.Invoke (System.Object obj, System.Object[] parameters) (at /Users/builduser/buildslave/mono-runtime-and-classlibs/build/mcs/class/corlib/System.Reflection/MethodBase.cs:115)
UnityEditor.SceneView.CallOnSceneGUI ()
UnityEditor.SceneView.HandleSelectionAndOnSceneGUI ()
UnityEditor.SceneView.OnGUI ()
System.Reflection.MonoMethod.Invoke (System.Object obj, BindingFlags invokeAttr, System.Reflection.Binder binder, System.Object[] parameters, System.Globalization.CultureInfo culture) (at /Users/builduser/buildslave/mono-runtime-and-classlibs/build/mcs/class/corlib/System.Reflection/MonoMethod.cs:222)
Hopefully the above can be of some help locating the cause of these issues.