Thank you LightSky
I have created the scrollview>grid> and added new prefabs via "NGUITools.AddChild(Parent, Prefab);" and works fine and fast

But i have now a few other questions.
How can i Position the prefab, should i add a Transformation on each AddChild() execution?
How can i Access the objects/UI elements in the prefab to polulate it with own text/Images etc. before it added to the grid?
Thank you for the help
MoPhat